

| Каталожный номер | HX012014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human EMP2 Polyclonal Antibody (HX012014) is a rabbit polyclonal antibody detecting Epithelial membrane protein 2; EMP-2; Protein XMP; EMP2; XMP in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Реактивность видов | Human | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant human EMP2 (Ile21-Thr67). | ||||||||
| Цель | Epithelial membrane protein 2; EMP-2; Protein XMP; EMP2; XMP | ||||||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P54851 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Epithelial membrane protein 2 (EMP2) is a ~19 kDa protein. Functions as a key regulator of cell membrane composition by regulating protein surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. Regulates transepithelial migration of neutrophils into the alveolar lumen, potentially via mediation of cell surface expression of adhesion markers and lipid raft formation. Negatively regulates caveolae formation by reducing CAV1 expression and CAV1 amount by increasing lysosomal degradation. Facilitates surface trafficking and formation of lipid rafts bearing GPI-anchor proteins. 1. Gee, HY. et al. (2014) American journal of human genetics 94, 884-90. PMID: 24814193 2. Wadehra, M. et al. (2005) Developmental biology 287, 336-45. PMID: 16216233 3. Morales, SA. et al. (2013) Investigative ophthalmology & visual science 54, 2367-72. PMID: 23439602 4. Fu, M. et al. (2011) PloS one 6, e19945. PMID: 21637765 5. Morales, SA. et al. (2012) Experimental eye research 102, 10-6. PMID: 22728127 6. Morales, SA. et al. (2009) Investigative ophthalmology & visual science 50, 4949-56. PMID: 19494199 7. Wilson, HL. et al. (2002) The Journal of biological chemistry 277, 34017-23. PMID: 12107182 8. Gordon, LK. et al. (2013) Oncogene 32, 5369-76. PMID: 23334331 9. Wadehra, M. et al. (2006) Developmental biology 292, 430-41. PMID: 16487956 | ||||||||
| Примечание | For research use only |

Lane 1: Mouse spleen lysate
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