

| Número de catálogo | HV625014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human FGF23 Polyclonal Antibody (HV625014) is a rabbit polyclonal antibody detecting FGF23 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human FGF23 (Ser180-Ile251). | ||||||||
| Objetivo | Phosphatonin, FGF-23, HYPF, FGF23, Fibroblast growth factor 23, Tumor-derived hypophosphatemia-inducing factor | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q9GZV9 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Fibroblast growth factor 23 (FGF23) is a ~27 kDa protein. Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Up-regulates EGR1 expression in the presence of KL. Acts directly on the parathyroid to decrease PTH secretion. Regulator of vitamin-D metabolism. 1. Unknown (2000) Nature genetics 26, 345-8. PMID: 11062477 2. Bowe, AE. et al. (2001) Biochemical and biophysical research communications 284, 977-81. PMID: 11409890 3. Shimada, T. et al. (2004) Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 19, 429-35. PMID: 15040831 4. Wang, H. et al. (2008) Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 23, 939-48. PMID: 18282132 | ||||||||
| Nota | For research use only. |




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