

| Numéro de catalogue | HS760025 |
|---|---|
| Description |
Anti-Human FSCN1 Monoclonal Antibody (1A595) [1A595] (HS760025) is a mouse monoclonal antibody detecting FSCN1 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| Reactivité des espèces | Human |
| Applications | ELISA, IHC, WB |
| Espèce hôte | Mouse |
| Clonalité | Monoclonal |
| Isotype | IgG |
| ID de clone | 1A595 |
| Immunogène | E. coli - derived recombinant human FSCN1 (Gln277-Gly396). |
| Cible | Fascin, 55 kDa actin-bundling protein, Singed-like protein, p55, FSCN1 |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Numéro d'accès | Q16658 |
| Forme | Liquid |
| Tampon de stockage | 0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Contexte | Fascin (FSCN1) is a ~54 kDa protein. Actin-binding protein that contains 2 major actin binding sites. Organizes filamentous actin into parallel bundles. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration. Mediates reorganization of the actin cytoskeleton and axon growth cone collapse in response to NGF. 1. Jansen, S. et al. (2011) The Journal of biological chemistry 286, 30087-96. PMID: 21685497 2. Yang, S. et al. (2013) The Journal of biological chemistry 288, 274-84. PMID: 23184945 3. Chen, L. et al. (2010) Nature 464, 1062-6. PMID: 20393565 4. Deinhardt, K. et al. (2011) Science signaling 4, ra82. PMID: 22155786 |
| Note | For research use only. |

SDS-PAGE for Anti-Human FSCN1 Monoclonal Antibody (1A595)




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