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Anti-Human Guanylyl Cyclase C/GUCY2C Recombinant Antibody (SAA2394) (HB626013)

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Anti-Human Guanylyl Cyclase C/GUCY2C Recombinant Antibody (SAA2394)
Anti-Human Guanylyl Cyclase C/GUCY2C Recombinant Antibody (SAA2394)
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  • 1mg
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Vista general
Número de catálogoHB626013
Descripción
Anti-Human Guanylyl Cyclase C/GUCY2C Recombinant Antibody (SAA2394) (HB626013) is a mouse monoclonal antibody detecting Guanylyl Cyclase C/GUCY2C in ELISA. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
Reactividad de especiesHuman
AplicacionesELISA
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG2a, kappa
ID de clonSAA2394
Objetivo Guanylyl cyclase C, GC-C, EC:4.6.1.2, Heat-stable enterotoxin receptor, STA receptor, hSTAR, Intestinal guanylate cyclase, GUCY2C, GUC2C, STAR
Nivel de endotoxinas < 10 EU/mg as determined by LAL method.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P25092
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:2000-1:20000
Fondo

Guanylyl cyclase C (GUCY2C) is a ~123 kDa protein. Guanylyl cyclase that catalyzes synthesis of cyclic GMP (cGMP) from GTP. Receptor for the E.coli heat-stable enterotoxin; E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GUCY2C. Also activated by the endogenous peptides guanylin and uroguanylin.

1. Scott, RO. et al. (2002) The Journal of biological chemistry 277, 22934-41. PMID: 11950846
2. Singh, S. et al. (1991) Biochemical and biophysical research communications 179, 1455-63. PMID: 1718270
3. Fiskerstrand, T. et al. (2012) The New England journal of medicine 366, 1586-95. PMID: 22436048
4. Romi, H. et al. (2012) American journal of human genetics 90, 893-9. PMID: 22521417
5. Arshad, N. et al. (2013) The Journal of biological chemistry 288, 3907-17. PMID: 23269669
6. de Sauvage, FJ. et al. (1991) The Journal of biological chemistry 266, 17912-8. PMID: 1680854
7. Mann, EA. et al. (1993) The American journal of physiology 264, G172-8. PMID: 8381596
Nota For research use only.
Isotype Control Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)
Imágenes
  • Anti-Human Guanylyl Cyclase C/GUCY2C Recombinant Antibody (SAA2394)

    SDS-PAGE

    SDS-PAGE for Anti-Human GUCY2C Antibody (SAA2394)

Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human Guanylyl Cyclase C/GUCY2C Recombinant Antibody (SAA2394)

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