

| Numéro de catalogue | HB626013 | ||||
|---|---|---|---|---|---|
| Description |
Anti-Human Guanylyl Cyclase C/GUCY2C Recombinant Antibody (SAA2394) (HB626013) is a mouse monoclonal antibody detecting Guanylyl Cyclase C/GUCY2C in ELISA. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||
| Applications | ELISA | ||||
| Espèce hôte | Mouse | ||||
| Clonalité | Monoclonal | ||||
| Isotype | IgG2a, kappa | ||||
| ID de clone | SAA2394 | ||||
| Cible | Guanylyl cyclase C, GC-C, EC:4.6.1.2, Heat-stable enterotoxin receptor, STA receptor, hSTAR, Intestinal guanylate cyclase, GUCY2C, GUC2C, STAR | ||||
| Niveau d'endotoxines | < 10 EU/mg as determined by LAL method. | ||||
| Pureté | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Numéro d'accès | P25092 | ||||
| Forme | Liquid | ||||
| Tampon de stockage | 0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Contexte | Guanylyl cyclase C (GUCY2C) is a ~123 kDa protein. Guanylyl cyclase that catalyzes synthesis of cyclic GMP (cGMP) from GTP. Receptor for the E.coli heat-stable enterotoxin; E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GUCY2C. Also activated by the endogenous peptides guanylin and uroguanylin. 1. Scott, RO. et al. (2002) The Journal of biological chemistry 277, 22934-41. PMID: 11950846 2. Singh, S. et al. (1991) Biochemical and biophysical research communications 179, 1455-63. PMID: 1718270 3. Fiskerstrand, T. et al. (2012) The New England journal of medicine 366, 1586-95. PMID: 22436048 4. Romi, H. et al. (2012) American journal of human genetics 90, 893-9. PMID: 22521417 5. Arshad, N. et al. (2013) The Journal of biological chemistry 288, 3907-17. PMID: 23269669 6. de Sauvage, FJ. et al. (1991) The Journal of biological chemistry 266, 17912-8. PMID: 1680854 7. Mann, EA. et al. (1993) The American journal of physiology 264, G172-8. PMID: 8381596 | ||||
| Note | For research use only. | ||||
| Isotype Control | Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023) |

SDS-PAGE for Anti-Human GUCY2C Antibody (SAA2394)




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