

| Número de catálogo | HB626023 |
|---|---|
| Descripción |
Anti-Human GUCY2C Nanobody (SAA2687) [SAA2687] (HB626023) is a alpaca monoclonal antibody detecting GUCY2C in ELISA. Suitable for Human.
|
| Reactividad de especies | Human |
| Aplicaciones | ELISA |
| Especie huésped | Alpaca |
| Clonalidad | Monoclonal |
| Isotipo | VHH-8His |
| ID de clon | SAA2687 |
| Objetivo | EC:4.6.1.2, GC-C, GUC2C, GUCY2C, Guanylyl cyclase C, Heat-stable enterotoxin receptor, Intestinal guanylate cyclase, STA receptor, STAR, hSTAR |
| Nivel de endotoxinas | < 10 EU/mg as determined by LAL method. |
| Pureza | >95% as determined by SDS-PAGE. |
| Purificación | Purified by Nickel column. |
| Número de acceso | P25092 |
| Forma | Liquid |
| Buffer de almacenamiento | 0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Fondo | Guanylyl cyclase C (GUCY2C) is a ~123 kDa protein. Guanylyl cyclase that catalyzes synthesis of cyclic GMP (cGMP) from GTP. Receptor for the E.coli heat-stable enterotoxin; E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GUCY2C. Also activated by the endogenous peptides guanylin and uroguanylin. 1. Scott, RO. et al. (2002) The Journal of biological chemistry 277, 22934-41. PMID: 11950846 2. Singh, S. et al. (1991) Biochemical and biophysical research communications 179, 1455-63. PMID: 1718270 3. Fiskerstrand, T. et al. (2012) The New England journal of medicine 366, 1586-95. PMID: 22436048 4. Romi, H. et al. (2012) American journal of human genetics 90, 893-9. PMID: 22521417 5. Arshad, N. et al. (2013) The Journal of biological chemistry 288, 3907-17. PMID: 23269669 6. de Sauvage, FJ. et al. (1991) The Journal of biological chemistry 266, 17912-8. PMID: 1680854 7. Mann, EA. et al. (1993) The American journal of physiology 264, G172-8. PMID: 8381596 |
| Nota | For research use only. |




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