Anti-Human IL-20 Recombinant Antibody (SAA0389) (HV989107)

Name: Anti-Human IL-20 Recombinant Antibody (SAA0389)
Brand: abinScience
SKU: HV989107
Price: 196 USD
Availability: InStock

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Numéro de catalogue	HV989107
Reactivité des espèces	Human
Applications	ELISA, FCM
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG1, kappa
ID de clone	SAA0389
Cible	IL20, Cytokine Zcyto10, ZCYTO10, IL-20, Interleukin-20
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q9NYY1
Forme	Liquid
Tampon de stockage	0.01M PBS, pH 7.4, 0.09% Sodium azide. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte	Interleukin-20 (IL20) is a ~20 kDa protein. Pro-inflammatory and angiogenic cytokine mainly secreted by monocytes and skin keratinocytes that plays crucial roles in immune responses, regulation of inflammatory responses, hemopoiesis, as well as epidermal cell and keratinocyte differentiation. Enhances tissue remodeling and wound-healing activities and restores the homeostasis of epithelial layers during infection and inflammatory responses to maintain tissue integrity. Affects multiple actin-mediated functions in activated neutrophils leading to inhibition of phagocytosis, granule exocytosis, and migration. Exert its effects via the type I IL-20 receptor complex consisting of IL20RA and IL20RB. Alternatively, can mediate its activity through a second receptor complex called type II IL-20 receptor complex composed of IL22RA1 and IL20RB. 1. Sa, SM. et al. (2007) Journal of immunology (Baltimore, Md. : 1950) 178, 2229-40. PMID: 17277128 2. Hsu, YH. et al. (2021) Immunology 164, 817-833. PMID: 34403503 3. Gough, P. et al. (2017) Journal of immunology (Baltimore, Md. : 1950) 198, 4373-4382. PMID: 28424238 4. Wang, M. et al. (2002) The Journal of biological chemistry 277, 7341-7. PMID: 11706020 5. Dumoutier, L. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 3545-9. PMID: 11564763 6. Andrés, RM. et al. (2013) Experimental dermatology 22, 323-8. PMID: 23614738
Note	For research use only.

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SDS-PAGE for Anti-Human IL20 Antibody (SAA0389)

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Anti-Human IL-20 Recombinant Antibody (SAA0389).pdf

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