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| カタログ番号 | HF648117 |
|---|---|
| 種反応性 | Human |
| アプリケーション | FCM |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | IgG2, kappa |
| クローンID | SAA0176 |
| 抱合 | FITC |
| ターゲット | Immunoglobulin-like domain-containing receptor 2, ILDR2, C1orf32 |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 関連製品 | Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10), FITC |
| アクセッション番号 | Q71H61 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 背景 | Immunoglobulin-like domain-containing receptor 2 (ILDR2) is a ~71 kDa protein. May be involved in ER stress pathways with effects on lipid homeostasis and insulin secretion. With ILDR1 and LSR, involved in the maintain of the epithelial barrier function through the recruitment of MARVELD2/tricellulin to tricellular tight junctions. Also functions as a B7-like protein family member expressed on immune cells and inflamed tissue and with T-cell inhibitory activity. In the inner ear, may regulate alternative pre-mRNA splicing via binding to TRA2A, TRA2B and SRSF1. 1. Hecht, I. et al. (2018) Journal of immunology (Baltimore, Md. : 1950) 200, 2025-2037. PMID: 29431694 |
| 注意事項 | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |
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