Anti-Human Lgr5/GPR49 Recombinant Antibody (SAA0507) (HF614107)

Name: Anti-Human Lgr5/GPR49 Recombinant Antibody (SAA0507)
Brand: abinScience
SKU: HF614107
Price: 191 USD
Availability: InStock

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Обзор

Каталожный номер	HF614107
Реактивность видов	Human
Применения	FCM, IP, WB
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	IgG2a, kappa
ID клона	SAA0507
Цель	G-protein coupled receptor 49, G-protein coupled receptor HG38, LGR5, GPR67, GPR49, G-protein coupled receptor 67, Leucine-rich repeat-containing G-protein coupled receptor 5
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	O75473
Форма	Liquid
Буфер хранения	0.01M PBS, pH 7.4, 0.09% Sodium azide. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Фон	Leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5/GPR49) is a ~99 kDa protein. Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development.
Примечание	For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human LGR5/GPR49 Antibody (SAA0507)

Ссылки

Даташит

Anti-Human Lgr5/GPR49 Recombinant Antibody (SAA0507).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

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Stock Solution

C₁ (Stock Conc.)

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Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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