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Anti-Human PMEL17/ME20M Recombinant Antibody (17A9) (HW380013)

Anti-Human PMEL17/ME20M Recombinant Antibody (17A9)
Anti-Human PMEL17/ME20M Recombinant Antibody (17A9)
Precio(USD):
Especificación:
  • 20ug
  • 50ug
  • 100ug
  • 1mg
Número:
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Vista general
Número de catálogoHW380013
Reactividad de especiesHuman
AplicacionesELISA, FCM, IHC
Especie huéspedHuman
ClonalidadMonoclonal
IsotipoIgG1, kappa
ID de clon17A9
Objetivo Melanocyte protein PMEL, ME20-M, ME20M, Melanocyte protein Pmel 17, Melanocytes lineage-specific antigen GP100, Melanoma-associated ME20 antigen, P1, P100, Premelanosome protein, Silver locus protein homolog, M-alpha, 95 kDa melanocyte-specific secreted glycoprotein, P26, Secreted melanoma-associated ME20 antigen, ME20-S, ME20S, M-beta, PMEL, D12S53E, PMEL17, SILV
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P40967
RRID Anti-Human PMEL17/ME20M Antibody (17A9) (abinScience Cat# HW380013, RRID:AB_3729455)
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:2000-1:20000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

Melanocyte protein PMEL (PMEL17/ME20M) is a ~70 kDa protein. Forms physiological amyloids that play a central role in melanosome morphogenesis and pigmentation. The maturation of unpigmented premelanosomes from stage I to II is marked by assembly of processed amyloidogenic fragments into parallel fibrillar sheets, which elongate the vesicle into a striated ellipsoidal shape. In pigmented stage III and IV melanosomes, the amyloid matrix serves as a platform where eumelanin precursors accumulate at high local concentrations for pigment formation. May prevent pigmentation-associated toxicity by sequestering toxic reaction intermediates of eumelanin biosynthesis pathway.

Nota For research use only.
Isotype Control Human IgG1 (LALA) Recombinant Isotype Control Antibody (HyHEL-10) (HP688107)
Imágenes
  • Anti-Human PMEL17/ME20M Recombinant Antibody (17A9)

    SDS-PAGE

    SDS-PAGE for Anti-Human PMEL17/ME20M Antibody (17A9).

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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