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Anti-Human PMEL17/ME20M Recombinant Antibody (17A9) (HW380013)

Anti-Human PMEL17/ME20M Recombinant Antibody (17A9)
Anti-Human PMEL17/ME20M Recombinant Antibody (17A9)
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Aperçu
Numéro de catalogueHW380013
Reactivité des espècesHuman
ApplicationsELISA, FCM, IHC
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG1, kappa
ID de clone17A9
Cible Melanocyte protein PMEL, ME20-M, ME20M, Melanocyte protein Pmel 17, Melanocytes lineage-specific antigen GP100, Melanoma-associated ME20 antigen, P1, P100, Premelanosome protein, Silver locus protein homolog, M-alpha, 95 kDa melanocyte-specific secreted glycoprotein, P26, Secreted melanoma-associated ME20 antigen, ME20-S, ME20S, M-beta, PMEL, D12S53E, PMEL17, SILV
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P40967
RRID Anti-Human PMEL17/ME20M Antibody (17A9) (abinScience Cat# HW380013, RRID:AB_3729455)
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:2000-1:20000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

Melanocyte protein PMEL (PMEL17/ME20M) is a ~70 kDa protein. Forms physiological amyloids that play a central role in melanosome morphogenesis and pigmentation. The maturation of unpigmented premelanosomes from stage I to II is marked by assembly of processed amyloidogenic fragments into parallel fibrillar sheets, which elongate the vesicle into a striated ellipsoidal shape. In pigmented stage III and IV melanosomes, the amyloid matrix serves as a platform where eumelanin precursors accumulate at high local concentrations for pigment formation. May prevent pigmentation-associated toxicity by sequestering toxic reaction intermediates of eumelanin biosynthesis pathway.

Note For research use only.
Isotype Control Human IgG1 (LALA) Recombinant Isotype Control Antibody (HyHEL-10) (HP688107)
Images
  • Anti-Human PMEL17/ME20M Recombinant Antibody (17A9)

    SDS-PAGE

    SDS-PAGE for Anti-Human PMEL17/ME20M Antibody (17A9).

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Volume
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g/mol
Formula
C₁ × V₁ = C₂ × V₂
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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Recommandation

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