Anti-Human PRMT3 IP Recombinant Antibody (SAA0218) (HT002013)

Name: Anti-Human PRMT3 IP Recombinant Antibody (SAA0218)
Brand: abinScience
SKU: HT002013
Price: 191 USD
Availability: InStock

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Цена(USD):

Спецификация:

50ug
100ug
1mg

Количество:

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HT002013

Реактивность видов

Human

Применения

ELISA, IF, IP, WB

Хозяинский вид

Mouse

Клоональность

Monoclonal

Изотип

IgG1, kappa

ID клона

SAA0218

Цель

PRMT3, HRMT1L3, Protein arginine N-methyltransferase 3, Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

O60678

RRID

Anti-Human PRMT3 IP Antibody (SAA0218) (abinScience Cat# HT002013, RRID:AB_3729752)

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Фон

Protein arginine N-methyltransferase 3 (PRMT3) is a ~59 kDa protein. Protein-arginine N-methyltransferase that catalyzes both the monomethylation and asymmetric dimethylation of the guanidino nitrogens of arginine residues in target proteins, and therefore falls into the group of type I methyltransferases. Catalyzes the asymmetric arginine dimethylation at multiple sites in the Arg/Gly-rich region of small ribosomal subunit protein uS5/RPS2. Also appears to methylate other ribosomal proteins. May regulate retinoic acid synthesis and signaling by inhibiting ALDH1A1 retinal dehydrogenase activity. Contributes to methylation of histone H4 'Arg-3', a specific tag for epigenetic transcriptional activation.

1. Siarheyeva, A. et al. (2012) Structure (London, England : 1993) 20, 1425-35. PMID: 22795084

2. Liu, F. et al. (2013) Journal of medicinal chemistry 56, 2110-24. PMID: 23445220

3. Kaniskan, HÜ. et al. (2015) Angewandte Chemie (International ed. in English) 54, 5166-70. PMID: 25728001

4. Min, Z. et al. (2019) Cell death & disease 10, 581. PMID: 31378783

5. Verma, M. et al. (2021) Communications biology 4, 109. PMID: 33495566

6. Gupta, S. et al. (2024) The Biochemical journal 481, 1723-1740. PMID: 39513743

Примечание

For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human PRMT3 IP Antibody (SAA0218)

Ссылки

Даташит

Anti-Human PRMT3 IP Recombinant Antibody (SAA0218).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа