Anti-Human ROR1 Recombinant Antibody (R12) (HX065307)

Name: Anti-Human ROR1 Recombinant Antibody (R12)
Brand: abinScience
SKU: HX065307
Price: 191 USD
Availability: InStock

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概要
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参考文献
データシート
SDS

概要

カタログ番号	HX065307
種反応性	Human
アプリケーション	FCM
宿主種	Mouse
クローン性	Monoclonal
アイソタイプ	IgG2a
クローンID	R12
テスト済みアプリケーション	WB
ターゲット	Neurotrophic tyrosine kinase, receptor-related 1, Inactive tyrosine-protein kinase transmembrane receptor ROR1, NTRKR1, ROR1
エンドトキシンレベル	Please contact with the lab for this information.
純度	>95% as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	Q01973
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Inactive tyrosine-protein kinase transmembrane receptor ROR1 (NTRKR1) is a ~104 kDa protein. Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling. In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells. Via IGFBP5 ligand, forms a complex with ERBB2 to enhance CREB oncogenic signaling. 1. Bainbridge, TW. et al. (2014) PloS one 9, e102695. PMID: 25029443 2. Diaz-Horta, O. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, 5993-8. PMID: 27162350 3. Lin, W. et al. (2023) Nature communications 14, 1578. PMID: 36949068
注意事項	For research use only.

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Bioactivity

Detects ROR1 in indirect ELISA.
Western blot

Western blot analysis was performed using anti-ROR1 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human ROR1 (Catalog No: HX065011)
Lane 2: negative control
Western blot

Western blot analysis was performed using anti-ROR1 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human ROR1 (Catalog No: HX065011)
Lane 2: negative control