Anti-Human ROR1 Recombinant Antibody (XBR1-402) (HX065023)

Name: Anti-Human ROR1 Recombinant Antibody (XBR1-402)
Brand: abinScience
SKU: HX065023
Price: 196 USD
Availability: InStock

Datasheet Compartir producto Copiar información

Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HX065023

Reactividad de especies

Human

Aplicaciones

ELISA, FCM

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG2a

ID de clon

XBR1-402

Objetivo

Neurotrophic tyrosine kinase, receptor-related 1, Inactive tyrosine-protein kinase transmembrane receptor ROR1, NTRKR1, ROR1

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

Q01973

RRID

Anti-Human ROR1/NTRKR1 Antibody (XBR1-402) (abinScience Cat# HX065023, RRID:AB_3729099)
_x005F_x005F_x000D_

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Inactive tyrosine-protein kinase transmembrane receptor ROR1 (NTRKR1) is a ~104 kDa protein. Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling. In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells. Via IGFBP5 ligand, forms a complex with ERBB2 to enhance CREB oncogenic signaling.

1. Bainbridge, TW. et al. (2014) PloS one 9, e102695. PMID: 25029443

2. Diaz-Horta, O. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, 5993-8. PMID: 27162350

3. Lin, W. et al. (2023) Nature communications 14, 1578. PMID: 36949068

Nota

For research use only.

Imágenes