Anti-Human ROR1 Recombinant Antibody (XBR1-402) (HX065023)

Name: Anti-Human ROR1 Recombinant Antibody (XBR1-402)
Brand: abinScience
SKU: HX065023
Price: 196 USD
Availability: InStock

Fiche technique Partager le produit Copier les informations

Prix(USD) :

Spécification :

50ug
100ug
1mg

Nombre :

Contactez-nous

Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HX065023

Reactivité des espèces

Human

Applications

ELISA, FCM

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a

ID de clone

XBR1-402

Cible

Neurotrophic tyrosine kinase, receptor-related 1, Inactive tyrosine-protein kinase transmembrane receptor ROR1, NTRKR1, ROR1

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q01973

RRID

Anti-Human ROR1/NTRKR1 Antibody (XBR1-402) (abinScience Cat# HX065023, RRID:AB_3729099)
_x005F_x005F_x000D_

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Inactive tyrosine-protein kinase transmembrane receptor ROR1 (NTRKR1) is a ~104 kDa protein. Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling. In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells. Via IGFBP5 ligand, forms a complex with ERBB2 to enhance CREB oncogenic signaling.

1. Bainbridge, TW. et al. (2014) PloS one 9, e102695. PMID: 25029443

2. Diaz-Horta, O. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, 5993-8. PMID: 27162350

3. Lin, W. et al. (2023) Nature communications 14, 1578. PMID: 36949068

Note

For research use only.

Images