Please ensure Javascript is enabled for purposes of website accessibility
Contáctenos Contáctenos
ES
Inicio > Productos > Anticuerpos > Anticuerpos Primarios

Anti-Human R-Spondin 2 Polyclonal Antibody (HA089014)

Datasheet Compartir producto Copiar información
Precio(USD): --
Especificación:
  • 50ug
  • 100ug
Número:
Contáctenos

  • Vista general

  • Imágenes

  • Referencias

  • Datasheet

  • SDS

Vista general
Número de catálogoHA089014
Descripción
Anti-Human RSPO2 Polyclonal Antibody (HA089014) is a rabbit polyclonal antibody detecting RSPO2. Suitable for Human and Mouse.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human RSPO2 (Ser36-Gln243).
Objetivo R-spondin-2, RSPO2, Roof plate-specific spondin-2, hRspo2
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Purified by antigen affinity column.
Número de acceso Q6UXX9
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

R-spondin-2 (RSPO2) is a ~28 kDa protein. Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. During embryonic development, plays a crucial role in limb specification, amplifying the Wnt signaling pathway independently of LGR4-6 receptors, possibly by acting as a direct antagonistic ligand to RNF43 and ZNRF3, hence governing the number of limbs an embryo should form.

1. de Lau, W. et al. (2011) Nature 476, 293-7. PMID: 21727895
2. Glinka, A. et al. (2011) EMBO reports 12, 1055-61. PMID: 21909076
3. Gong, X. et al. (2012) PloS one 7, e37137. PMID: 22615920
4. Szenker-Ravi, E. et al. (2018) Nature 557, 564-569. PMID: 29769720
Nota For research use only
Imágenes
Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recomendación

Contáctenos para cotizaciones personalizadas, solicitudes en masa y cualquier otro problema.

Correo: [email protected]

Lista de distribuidores

Obtener una cotización gratuita
Anti-Human R-Spondin 2 Polyclonal Antibody

Acceso rápido

Contáctenos

  • +86-027-65523339

  • [email protected]

  • Edificio C, No. 666, Calle Shendunsi, Wuhan, 430206, China

  • linkedin
  • Ins
  • youtube
  • youtube
Derechos de autor © 2026 abinScience. Todos los derechos reservados. Todos los productos son solo para uso de investigación