Anti-Human TMPRSS6 Recombinant Antibody (REGN8023) (HA025023)

Name: Anti-Human TMPRSS6 Recombinant Antibody (REGN8023)
Brand: abinScience
SKU: HA025023
Price: 191 USD
Availability: InStock

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Spécification :

50ug
100ug
1mg

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HA025023

Reactivité des espèces

Human

Applications

ELISA, FCM

Espèce hôte

Human

Clonalité

Monoclonal

Isotype

IgG4, kappa

ID de clone

REGN8023

Cible

Transmembrane protease serine 6, EC:3.4.21.-, Matriptase-2, TMPRSS6

Niveau d'endotoxines

< 10 EU/mg

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q8IU80

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Transmembrane protease serine 6 (TMPRSS6) is a ~90 kDa protein. Membrane-bound serine protease. Through the cleavage of cell surface hemojuvelin (HJV), a regulator of the expression of the iron absorption-regulating hormone hepicidin/HAMP, plays a role in iron homeostasis.

1. Silvestri, L. et al. (2008) Cell metabolism 8, 502-11. PMID: 18976966

2. Stirnberg, M. et al. (2010) The Biochemical journal 430, 87-95. PMID: 20518742

3. De Falco, L. et al. (2014) Human mutation 35, 1321-9. PMID: 25156943

4. McDonald, CJ. et al. (2015) American journal of physiology. Cell physiology 308, C539-47. PMID: 25588876

5. Finberg, KE. et al. (2008) Nature genetics 40, 569-71. PMID: 18408718

Note

For research use only

Images

SDS-PAGE

SDS-PAGE for Anti-Human TMPRSS6 Recombinant Antibody (REGN8023)

Reférences

Fiche technique

Anti-Human TMPRSS6 Recombinant Antibody (REGN8023).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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