Anti-Human VIPR1/VPAC1 Recombinant Antibody (23A11), PerCP (HB111147)

Name: Anti-Human VIPR1/VPAC1 Recombinant Antibody (23A11), PerCP
Brand: abinScience
SKU: HB111147
Price: 268 USD
Availability: InStock

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Каталожный номер	HB111147
Реактивность видов	Human
Применения	FCM, WB
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	IgG2a, kappa
ID клона	23A11
Конъюгация	PerCP
Цель	VIP-R-1, PACAP-R2, VIPR1, PACAP-R-2, Pituitary adenylate cyclase-activating polypeptide type II receptor, PACAP type II receptor, VPAC1, Vasoactive intestinal polypeptide receptor 1
Уровень эндотоксинов	Please contact with the lab for this information.
Связанные продукты	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), PerCP
Номер доступа	P32241
Форма	Liquid
Буфер хранения	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Store at 4°C for 12 months. Protect from light. Do not freeze.
Фон	Vasoactive intestinal polypeptide receptor 1 (VIPR1/VPAC1) is a ~51 kDa protein. G protein-coupled receptor activated by the neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP). Binds VIP and both PACAP27 and PACAP38 bioactive peptides with the following order of ligand affinity VIP = PACAP27 > PACAP38. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. Activates cAMP-dependent pathway. 1. Xu, Y. et al. (2022) Nature communications 13, 2272. PMID: 35477937 2. Piper, SJ. et al. (2022) Nature communications 13, 7013. PMID: 36385145 3. Couvineau, A. et al. (1994) Biochemical and biophysical research communications 200, 769-76. PMID: 8179610
Примечание	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human VIPR1/VPAC1 Recombinant Antibody (23A11), PerCP.pdf

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