Anti-Human VIPR1/VPAC1 Recombinant Antibody (23A11) (HB111107)

Name: Anti-Human VIPR1/VPAC1 Recombinant Antibody (23A11)
Brand: abinScience
SKU: HB111107
Price: 191 USD
Availability: InStock

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Overview

Catalog No.	HB111107
Species reactivity	Human
Applications	FCM, SPR, WB
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	23A11
Clonality	Monoclonal
Target	VIP-R-1, PACAP-R2, VIPR1, PACAP-R-2, Pituitary adenylate cyclase-activating polypeptide type II receptor, PACAP type II receptor, VPAC1, Vasoactive intestinal polypeptide receptor 1
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P32241
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.09% Sodium azide. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Vasoactive intestinal polypeptide receptor 1 (VIPR1/VPAC1) is a ~51 kDa protein. G protein-coupled receptor activated by the neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP). Binds VIP and both PACAP27 and PACAP38 bioactive peptides with the following order of ligand affinity VIP = PACAP27 > PACAP38. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. Activates cAMP-dependent pathway. 1. Xu, Y. et al. (2022) Nature communications 13, 2272. PMID: 35477937 2. Piper, SJ. et al. (2022) Nature communications 13, 7013. PMID: 36385145 3. Couvineau, A. et al. (1994) Biochemical and biophysical research communications 200, 769-76. PMID: 8179610
Note	For research use only.

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SDS-PAGE for Anti-Human VIPR1/VPAC1 Antibody (23A11)

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Datasheet

Anti-Human VIPR1/VPAC1 Recombinant Antibody (23A11).pdf

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Anti-Human VIPR1/VPAC1 Recombinant Antibody (23A11) (HB111107)

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