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Anti-Human IL-20 Polyclonal Antibody (HV989014)

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Vista general
Número de catálogoHV989014
Descripción
Anti-IL20 Polyclonal Antibody (HV989014) is a rabbit polyclonal antibody detecting IL20 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human IL20 (Gly24-Glu176).
Objetivo IL20, Cytokine Zcyto10, ZCYTO10, IL-20, Interleukin-20
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Purified by antigen affinity column.
Número de acceso Q9NYY1
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Interleukin-20 (IL20) is a ~20 kDa protein. Pro-inflammatory and angiogenic cytokine mainly secreted by monocytes and skin keratinocytes that plays crucial roles in immune responses, regulation of inflammatory responses, hemopoiesis, as well as epidermal cell and keratinocyte differentiation. Enhances tissue remodeling and wound-healing activities and restores the homeostasis of epithelial layers during infection and inflammatory responses to maintain tissue integrity. Affects multiple actin-mediated functions in activated neutrophils leading to inhibition of phagocytosis, granule exocytosis, and migration. Exert its effects via the type I IL-20 receptor complex consisting of IL20RA and IL20RB. Alternatively, can mediate its activity through a second receptor complex called type II IL-20 receptor complex composed of IL22RA1 and IL20RB.

1. Sa, SM. et al. (2007) Journal of immunology (Baltimore, Md. : 1950) 178, 2229-40. PMID: 17277128
2. Hsu, YH. et al. (2021) Immunology 164, 817-833. PMID: 34403503
3. Gough, P. et al. (2017) Journal of immunology (Baltimore, Md. : 1950) 198, 4373-4382. PMID: 28424238
4. Wang, M. et al. (2002) The Journal of biological chemistry 277, 7341-7. PMID: 11706020
5. Dumoutier, L. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 3545-9. PMID: 11564763
6. Andrés, RM. et al. (2013) Experimental dermatology 22, 323-8. PMID: 23614738
Nota For research use only.
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Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human IL-20 Polyclonal Antibody

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