Please ensure Javascript is enabled for purposes of website accessibility
Contáctenos Contáctenos
ES
Inicio > Productos > Anticuerpos > Anticuerpos Primarios

Anti-KARS1 Polyclonal Antibody (HC295014)

Datasheet Compartir producto Copiar información
Precio(USD): --
Especificación:
  • 50ug
  • 100ug
Número:
Contáctenos

  • Vista general

  • Imágenes

  • Referencias

  • Datasheet

  • SDS

Vista general
Número de catálogoHC295014
Descripción
Anti-KARS1 Polyclonal Antibody (HC295014) is a rabbit polyclonal antibody detecting KARS1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Cricetulus griseus.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human KARS1 (Arg323-Arg553).
Objetivo KIAA0070, KARS, Lysyl-tRNA synthetase, LysRS, Lysine--tRNA ligase, KARS1
Purificación Purified by antigen affinity column.
Número de acceso Q15046
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Lysine--tRNA ligase (KARS1) is a ~68 kDa protein. Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity.

1. Guzzo, CM. et al. (2008) Biochemical and biophysical research communications 365, 718-23. PMID: 18029264
2. Guo, M. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 2331-6. PMID: 18272479
3. Shiba, K. et al. (1997) The Journal of biological chemistry 272, 22809-16. PMID: 9278442
4. Park, SG. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 6356-61. PMID: 15851690
5. Lee, YN. et al. (2004) Immunity 20, 145-51. PMID: 14975237
6. Yannay-Cohen, N. et al. (2009) Molecular cell 34, 603-11. PMID: 19524539
7. Ofir-Birin, Y. et al. (2013) Molecular cell 49, 30-42. PMID: 23159739
8. Zamecnik, PC. et al. (1966) Biochemical and biophysical research communications 24, 91-7. PMID: 5338216
Nota For research use only.
Imágenes
Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recomendación

Contáctenos para cotizaciones personalizadas, solicitudes en masa y cualquier otro problema.

Correo: [email protected]

Lista de distribuidores

Obtener una cotización gratuita
Anti-KARS1 Polyclonal Antibody

Acceso rápido

Contáctenos

  • +86-027-65523339

  • [email protected]

  • Edificio C, No. 666, Calle Shendunsi, Wuhan, 430206, China

  • linkedin
  • Ins
  • youtube
  • youtube
Derechos de autor © 2026 abinScience. Todos los derechos reservados. Todos los productos son solo para uso de investigación