Anti-KRT8/CK-8 Polyclonal Antibody (HY427014)

Name: Anti-KRT8/CK-8 Polyclonal Antibody
Brand: abinScience
SKU: HY427014
Price: 168 USD
Availability: InStock

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Aperçu

Numéro de catalogue

HY427014

Description

Anti-KRT8/CK-8 Polyclonal Antibody (HY427014) is a rabbit polyclonal antibody detecting KRT8 in ELISA, IHC, WB. Suitable for Mouse, Bovine, Human, Rat, and Xenopus laevis.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human KRT8/CK-8 (Gln90-Gln236).

Cible

Type-II keratin Kb8, CYK8, Keratin-8, KRT8, Keratin, type II cytoskeletal 8, Cytokeratin-8, CK-8, K8

Purification

Purified by antigen affinity column.

Numéro d'accès

P05787

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Keratin, type II cytoskeletal 8 (KRT8/CK-8) is a ~53 kDa protein. Required for the formation of KRT8/KRT18 filaments that are involved in ARHGEF40-mediated actin stress fiber formation and tensional force-induced stress fiber formation and reinforcement. Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.

1. Fujiwara, S. et al. (2016) Molecular biology of the cell 27, 954-66. PMID: 26823019

Note

For research use only.

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