Anti-Human KRT8/CK-8 Monoclonal Antibody (1A500) (HY427015)

Name: Anti-Human KRT8/CK-8 Monoclonal Antibody (1A500)
Brand: abinScience
SKU: HY427015
Price: 106 USD
Availability: InStock

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Overview

Catalog No.	HY427015
Description	Anti-Human KRT8/CK-8 Monoclonal Antibody (1A500) [1A500] (HY427015) is a mouse monoclonal antibody detecting CK-8 in ELISA, IHC, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications.
Species reactivity	Human
Applications	ELISA, IHC, WB
Host species	Mouse
Isotype	IgG
Clone ID	1A500
Clonality	Monoclonal
Immunogen	E. coli - derived recombinant human KRT8/CK-8 (Gln90-Gln236).
Target	Keratin type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, Type-II keratin Kb8, KRT8
Purification	Protein A/G purified from cell culture supernatant.
Accession	P05787
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Keratin, type II cytoskeletal 8 (KRT8/CK-8) is a ~53 kDa protein. Required for the formation of KRT8/KRT18 filaments that are involved in ARHGEF40-mediated actin stress fiber formation and tensional force-induced stress fiber formation and reinforcement. Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. 1. Fujiwara, S. et al. (2016) Molecular biology of the cell 27, 954-66. PMID: 26823019
Note	For research use only.