



| Catalog No. | HY427013 | ||||
|---|---|---|---|---|---|
| Description |
Anti-Human KRT8/CK-8 Recombinant Antibody (TS1) (HY427013) is a mouse monoclonal antibody detecting KRT8/CK-8 in FCM, IF, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||
| Applications | FCM, IF, IHC, WB | ||||
| Host species | Mouse | ||||
| Clonality | Monoclonal | ||||
| Isotype | IgG1, kappa | ||||
| Clone ID | TS1 | ||||
| Target | Type-II keratin Kb8, CYK8, Keratin-8, KRT8, Keratin, type II cytoskeletal 8, Cytokeratin-8, CK-8, K8 | ||||
| Endotoxin level | < 10 EU/mg as determined by LAL method. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | P05787 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Background | Keratin, type II cytoskeletal 8 (KRT8/CK-8) is a ~53 kDa protein. Required for the formation of KRT8/KRT18 filaments that are involved in ARHGEF40-mediated actin stress fiber formation and tensional force-induced stress fiber formation and reinforcement. Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. 1. Fujiwara, S. et al. (2016) Molecular biology of the cell 27, 954-66. PMID: 26823019 | ||||
| Note | For research use only. |

SEC-HPLC detection for Anti-Human KRT8/CK-8 Antibody (TS1).

SDS-PAGE for Anti-Human KRT8/CK-8 Antibody (TS1).




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