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Anti-Mouse MDR1/ABCB1 Recombinant Antibody (SAA0482) (MY466107)

Anti-Mouse MDR1/ABCB1 Recombinant Antibody (SAA0482)
Anti-Mouse MDR1/ABCB1 Recombinant Antibody (SAA0482)
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Aperçu
Numéro de catalogueMY466107
MarqueabinScience
Reactivité des espècesHuman, Mouse, Hamster
ApplicationsELISA, FCM, IHC
Espèce hôteRat
ClonalitéMonoclonal
IsotypeIgG1, kappa
ID de cloneSAA0482
Cible Phospholipid transporter ABCB1, MDR1, CD243, ATP-binding cassette sub-family B member 1, ABCB1, Multidrug resistance protein 1, P-glycoprotein 1, ATP-dependent translocase ABCB1, PGY1, P-Glycoprotein, P Glycoprotein
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P21447
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

ATP-dependent translocase ABCB1 (CD243) is a ~140 kDa protein. Translocates drugs and phospholipids across the membrane. Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins. Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.

1. van Helvoort, A. et al. (1996) Cell 87, 507-17. PMID: 8898203
Note For research use only.
Images
  • Anti-Mouse MDR1/ABCB1 Recombinant Antibody (SAA0482)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse CD243/P-Glycoprotein Antibody (SAA0482)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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