

| Catalog No. | MY466137 |
|---|---|
| Species reactivity | Hamster |
| Applications | ELISA, FCM |
| Host species | Rat |
| Isotype | IgG1, kappa |
| Clone ID | SAA0482 |
| Conjugation | APC |
| Clonality | Monoclonal |
| Target | Phospholipid transporter ABCB1, MDR1, CD243, ATP-binding cassette sub-family B member 1, ABCB1, Multidrug resistance protein 1, P-glycoprotein 1, ATP-dependent translocase ABCB1, PGY1, P-Glycoprotein, P Glycoprotein |
| Endotoxin level | Please contact with the lab for this information. |
| Associated products | Rat IgG1, kappa Recombinant Isotype Control Antibody (ES26-14D1.11), APC |
| Accession | P21447 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Background | ATP-dependent translocase ABCB1 (CD243) is a ~140 kDa protein. Translocates drugs and phospholipids across the membrane. Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins. Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. 1. van Helvoort, A. et al. (1996) Cell 87, 507-17. PMID: 8898203 |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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