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Anti-Mouse CD243/P-Glycoprotein Recombinant Antibody (SAA0482) (MY466107)

Anti-Mouse CD243/P-Glycoprotein Recombinant Antibody (SAA0482)
Anti-Mouse CD243/P-Glycoprotein Recombinant Antibody (SAA0482)
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Overview
Catalog No.MY466107
Species reactivityHamster
ApplicationsELISA, FCM, IHC
Host speciesRat
IsotypeIgG1, kappa
Clone IDSAA0482
Clonality Monoclonal
Target Phospholipid transporter ABCB1, MDR1, CD243, ATP-binding cassette sub-family B member 1, ABCB1, Multidrug resistance protein 1, P-glycoprotein 1, ATP-dependent translocase ABCB1, PGY1, P-Glycoprotein, P Glycoprotein
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P21447
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

ATP-dependent translocase ABCB1 (CD243) is a ~140 kDa protein. Translocates drugs and phospholipids across the membrane. Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins. Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.

1. van Helvoort, A. et al. (1996) Cell 87, 507-17. PMID: 8898203
Note For research use only.
Images
  • Anti-Mouse CD243/P-Glycoprotein Recombinant Antibody (SAA0482)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse CD243/P-Glycoprotein Antibody (SAA0482)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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