

| Catalog No. | MY466107 |
|---|---|
| Species reactivity | Hamster |
| Applications | ELISA, FCM, IHC |
| Host species | Rat |
| Isotype | IgG1, kappa |
| Clone ID | SAA0482 |
| Clonality | Monoclonal |
| Target | Phospholipid transporter ABCB1, MDR1, CD243, ATP-binding cassette sub-family B member 1, ABCB1, Multidrug resistance protein 1, P-glycoprotein 1, ATP-dependent translocase ABCB1, PGY1, P-Glycoprotein, P Glycoprotein |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P21447 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Background | ATP-dependent translocase ABCB1 (CD243) is a ~140 kDa protein. Translocates drugs and phospholipids across the membrane. Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins. Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. 1. van Helvoort, A. et al. (1996) Cell 87, 507-17. PMID: 8898203 |
| Note | For research use only. |

SDS-PAGE for Anti-Mouse CD243/P-Glycoprotein Antibody (SAA0482)




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