Anti-Mouse PD-L1 Recombinant Nanobody (C3) (MV974033)

Name: Anti-Mouse PD-L1 Recombinant Nanobody (C3)
Brand: abinScience
SKU: MV974033
Price: 191 USD
Availability: InStock

Datasheet Compartir producto Copiar información

Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

MV974033

Descripción

Anti-Mouse CD274/PD-L1/B7-H1 Nanobody (C3) [C3] (MV974033) is a alpaca monoclonal antibody detecting B7-H1 in ELISA, FuncS. Suitable for Mouse.

Reactividad de especies

Mouse

Aplicaciones

ELISA, FuncS, WB

Especie huésped

Alpaca

Clonalidad

Monoclonal

Isotipo

VHH-8His-Cys-tag

ID de clon

Aplicaciones probadas

Objetivo

B7 homolog 1, B7-H1, B7H1, CD274, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, PDL1, Programmed cell death 1 ligand 1, Programmed death ligand 1

Nivel de endotoxinas

< 10 EU/mg

Pureza

>95% as determined by SDS-PAGE.

Purificación

Purified by Nickel column.

Número de acceso

Q9EP73

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Programmed cell death 1 ligand 1 (CD274/PD-L1) is a ~32 kDa protein. Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response. Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10). CD274 is the therapeutic target of atezolizumab (Tecentriq) and durvalumab (Imfinzi).

1. Tamura, H. et al. (2001) Blood 97, 1809-16. PMID: 11238124

2. Freeman, GJ. et al. (2000) The Journal of experimental medicine 192, 1027-34. PMID: 11015443

3. Wang, S. et al. (2003) The Journal of experimental medicine 197, 1083-91. PMID: 12719480

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Mouse CD274/PD-L1/B7-H1 Nanobody (C3)
Bioactivity

Detects recombinant mouse PDL1 (Catalog No: MV974011) in indirect ELISA.
Western blot

Western blot analysis was performed using anti-PDL1 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant mouse PDL1 (Catalog No: MV974011)