Anti-Mouse Transferrin R/TfR Recombinant Antibody (8D3) (MY036307)

Name: Anti-Mouse Transferrin R/TfR Recombinant Antibody (8D3)
Brand: abinScience
SKU: MY036307
Price: 196 USD
Availability: InStock

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Vista general

Número de catálogo	MY036307
Reactividad de especies	Mouse
Aplicaciones	FCM, FuncS, ICC, IF, IHC, IHC-Fr
Especie huésped	Rat
Clonalidad	Monoclonal
Isotipo	IgG2a, kappa
ID de clon	8D3
Objetivo	CD71, T9, TFRC, TR, TfR, TfR1, Transferrin receptor 1, Transferrin receptor protein 1, Transferrin receptor protein 1, serum form, Trfr, p90, sTfR
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	Q62351
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo	Transferrin receptor protein 1 (CD71/TFRC) is a ~85 kDa protein. Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Upon stimulation, positively regulates T and B cell proliferation through iron uptake. 1. Jabara, HH. et al. (2016) Nature genetics 48, 74-8. PMID: 26642240 2. Yang, J. et al. (2024) The Journal of clinical investigation 134. PMID: 38625739
Nota	For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Mouse CD71/TFRC Antibody (8D3)

Referencias

Datasheet

Anti-Mouse Transferrin R/TfR Recombinant Antibody (8D3).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Mass

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Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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