Anti-Mouse Transferrin R/TfR Recombinant Antibody (8D3) (MY036307)

Name: Anti-Mouse Transferrin R/TfR Recombinant Antibody (8D3)
Brand: abinScience
SKU: MY036307
Price: 196 USD
Availability: InStock

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Aperçu

Numéro de catalogue	MY036307
Reactivité des espèces	Mouse
Applications	FCM, FuncS, ICC, IF, IHC, IHC-Fr
Espèce hôte	Rat
Clonalité	Monoclonal
Isotype	IgG2a, kappa
ID de clone	8D3
Cible	CD71, T9, TFRC, TR, TfR, TfR1, Transferrin receptor 1, Transferrin receptor protein 1, Transferrin receptor protein 1, serum form, Trfr, p90, sTfR
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q62351
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte	Transferrin receptor protein 1 (CD71/TFRC) is a ~85 kDa protein. Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Upon stimulation, positively regulates T and B cell proliferation through iron uptake. 1. Jabara, HH. et al. (2016) Nature genetics 48, 74-8. PMID: 26642240 2. Yang, J. et al. (2024) The Journal of clinical investigation 134. PMID: 38625739
Note	For research use only.

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SDS-PAGE

SDS-PAGE for Anti-Mouse CD71/TFRC Antibody (8D3)

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Anti-Mouse Transferrin R/TfR Recombinant Antibody (8D3).pdf

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