Anti-Mouse Dkk-1 Recombinant Antibody (MOR04454) (MF914013)

Name: Anti-Mouse Dkk-1 Recombinant Antibody (MOR04454)
Brand: abinScience
SKU: MF914013
Price: 126 USD
Availability: InStock

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

MF914013

Reactivité des espèces

Human, Mouse

Applications

ELISA

Espèce hôte

Rat

Clonalité

Monoclonal

Isotype

IgG1, kappa

ID de clone

MOR04454

Cible

Dickkopf-1, SK, hDkk-1, Dkk-1, Dickkopf-related protein 1, DKK1

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

O54908

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Dickkopf-related protein 1 (DKK1) is a ~29 kDa protein. Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity. Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning.

1. Chen, L. et al. (2008) The Journal of biological chemistry 283, 23364-70. PMID: 18524778

2. Causeret, F. et al. (2016) Cell death and differentiation 23, 323-32. PMID: 26206087

3. Ellwanger, K. et al. (2008) Molecular and cellular biology 28, 4875-82. PMID: 18505822

Note

For research use only.

Isotype Control

Rat IgG1, kappa Recombinant Isotype Control Antibody (RTK2071) (RV080407)

Images

SDS-PAGE

SDS-PAGE for Anti-Mouse DKK1 Antibody (MOR04454)

Reférences

Fiche technique

Anti-Mouse Dkk-1 Recombinant Antibody (MOR04454).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai