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Anti-Mouse IL-22 Recombinant Antibody (356A11) (MV999023)

Anti-Mouse IL-22 Recombinant Antibody (356A11)
Anti-Mouse IL-22 Recombinant Antibody (356A11)
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  • 1mg
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Aperçu
Numéro de catalogueMV999023
Description
Anti-Mouse IL-22 Recombinant Antibody (356A11) (MV999023) is a mouse monoclonal antibody detecting IL-22 in Blocking, ELISA, FCM. Suitable for Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactivité des espècesMouse
ApplicationsBlocking, ELISA, FCM
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG1, lambda
ID de clone356A11
Cible Interleukin-22, Cytokine Zcyto18, IL-22, ZCYTO18, IL22, ILTIF, IL-TIF, IL-10-related T-cell-derived-inducible factor
Niveau d'endotoxines < 10 EU/mg as determined by LAL method.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès Q9JJY9
RRID Anti-Mouse IL22 Antibody (356A11) (abinScience Cat# MV999023, RRID:AB_3725831)
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:2000-1:20000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

Interleukin-22 (Interleukin-22,Cytokine Zcyto18,IL-22,ZCYTO18,IL22,ILTIF,IL-TIF,IL-10-related T-cell-derived-inducible factor) is a ~20 kDa protein. Cytokine that plays a critical role in modulating tissue responses during inflammation. Plays an essential role in the regeneration of epithelial cells to maintain barrier function after injury and for the prevention of further tissue damage. Unlike most of the cytokines, has no effect on immune cells. Signals through a heterodimeric receptor composed of two subunits, the specific receptor IL22RA1 which is present on non-immune cells in many organs and the shared subunit IL10RB. Ligation of IL22RA1 with IL22 induces activation of the tyrosine kinases JAK1 and TYK2, which in turn activates STAT3.

1. Brand, S. et al. (2007) American journal of physiology. Gastrointestinal and liver physiology 292, G1019-28. PMID: 17204547
2. Xie, MH. et al. (2000) The Journal of biological chemistry 275, 31335-9. PMID: 10875937
3. Jones, BC. et al. (2008) Structure (London, England : 1993) 16, 1333-44. PMID: 18599299
4. Akil, H. et al. (2015) PloS one 10, e0119872. PMID: 25793261
5. Moniruzzaman, M. et al. (2019) International journal of molecular sciences 20. PMID: 31311100
Note For research use only.
Isotype Control Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207)
Images
  • Anti-Mouse IL-22 Recombinant Antibody (356A11)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse IL22 Antibody (356A11).

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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