Anti-Mouse IL22 Recombinant Antibody (368D04) (MV999013)

Name: Anti-Mouse IL22 Recombinant Antibody (368D04)
Brand: abinScience
SKU: MV999013
Price: 196 USD
Availability: InStock

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1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

MV999013

Species reactivity

Human, Mouse

Applications

ELISA, FCM

Host species

Rat

Isotype

IgG2a, kappa

Clone ID

368D04

Clonality

Monoclonal

Target

Interleukin-22, Cytokine Zcyto18, IL-22, ZCYTO18, IL22, ILTIF, IL-TIF, IL-10-related T-cell-derived-inducible factor

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9JJY9

RRID

Anti-Mouse IL22 Antibody (368D04) (abinScience Cat# MV999013, RRID:AB_3725662)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Interleukin-22 (IL22) is a ~20 kDa protein. Cytokine that plays a critical role in modulating tissue responses during inflammation. Plays an essential role in the regeneration of epithelial cells to maintain barrier function after injury and for the prevention of further tissue damage. Unlike most of the cytokines, has no effect on immune cells. Signals through a heterodimeric receptor composed of two subunits, the specific receptor IL22RA1 which is present on non-immune cells in many organs and the shared subunit IL10RB. Ligation of IL22RA1 with IL22 induces activation of the tyrosine kinases JAK1 and TYK2, which in turn activates STAT3.

1. Saxton, RA. et al. (2021) Immunity 54, 660-672.e9. PMID: 33852830

2. Ulu, A. et al. (2022) Toxicology and applied pharmacology 446, 116044. PMID: 35525330

3. Delbue, D. et al. (2021) Frontiers in medicine 8, 656047. PMID: 33912578

4. Weathington, NM. et al. (2014) The Journal of biological chemistry 289, 17610-9. PMID: 24742671

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Mouse IL22 Antibody (368D04)

References

Datasheet

Anti-Mouse IL22 Recombinant Antibody (368D04).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Mouse IL22 Recombinant Antibody (368D04) (MV999013)

Overview

Images

References

Datasheet

SDS

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