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Anti-Mouse IL24 Recombinant Antibody (SAA2230) (MC472013)

Anti-Mouse IL24 Recombinant Antibody (SAA2230)
Anti-Mouse IL24 Recombinant Antibody (SAA2230)
Anti-Mouse IL24 Recombinant Antibody (SAA2230)
Anti-Mouse IL24 Recombinant Antibody (SAA2230)
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Aperçu
Numéro de catalogueMC472013
Reactivité des espècesHuman, Mouse
ApplicationsELISA, Blocking
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG1, lambda
ID de cloneSAA2230
Cible IL24
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès Q925S4
RRID Anti-Mouse IL24 antibody (SAA2230) (abinScience Cat# MC472013, RRID:AB_3729826)
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:2000-1:20000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Noms alternatifsMDA7, MDA-7, ST16, IL-24, Melanoma differentiation-associated gene 7 protein, Suppression of tumorigenicity 16 protein, IL24, Interleukin-24
Contexte

Interleukin-24 (IL24) is a ~25 kDa protein. Multifunctional cytokine mainly produced by T-cells that plays a regulatory role in immune response, tissue homeostasis, host defense, and oncogenesis. Possesses antiviral functions and induces the type I interferon response during influenza infection. Signals through two receptor complexes IL20RA/IL20RB or IL20RB/IL22RA1. In turn, stimulates the JAK1-STAT3 and MAPK pathways and promotes the secretion of pro-inflammatory mediators including IL8 and MMP1. Intracellularly, maintains endoplasmic reticulum homeostasis by restricting the eIF2alpha-CHOP pathway-mediated stress signal.

1. Wang, J. et al. (2020) Cell death & disease 11, 17. PMID: 31907348
2. Davidson, S. et al. (2022) Science immunology 7, eabi6763. PMID: 35148201
Note For research use only.
Isotype Control Human IgG1, lambda Isotype Control antibody (HyHEL-10) (HP248107)
Images
  • Anti-Mouse IL24 Recombinant Antibody (SAA2230)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse IL24 antibody (SAA2230)

  • Anti-Mouse IL24 Recombinant Antibody (SAA2230)

    Bioactivity

    Detects recombinant mouse IL24 (Catalog No: MC472012) in indirect ELISA

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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