Anti-Mouse IL24 Recombinant Antibody (SAA2595) (MC472023)

Name: Anti-Mouse IL24 Recombinant Antibody (SAA2595)
Brand: abinScience
SKU: MC472023
Price: 191 USD
Availability: InStock

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Overview

Catalog No.	MC472023
Species reactivity	Mouse
Applications	ELISA, FCM, Neutralization
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	SAA2595
Clonality	Monoclonal
Target	IL-24, IL-4-induced secreted protein, Il24, Interleukin-24, MDA-7, Mda7, Melanoma differentiation-associated gene 7 protein, Th2-specific cytokine FISP
Endotoxin level	<10 EU/mg
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q925S4
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Interleukin-24 (IL24) is a ~25 kDa protein. Multifunctional cytokine mainly produced by T-cells that plays a regulatory role in immune response, tissue homeostasis, host defense, and oncogenesis. Possesses antiviral functions and induces the type I interferon response during influenza infection. Signals through two receptor complexes IL20RA/IL20RB or IL20RB/IL22RA1. In turn, stimulates the JAK1-STAT3 and MAPK pathways and promotes the secretion of pro-inflammatory mediators including IL8 and MMP1. Intracellularly, maintains endoplasmic reticulum homeostasis by restricting the eIF2alpha-CHOP pathway-mediated stress signal. 1. Wang, J. et al. (2020) Cell death & disease 11, 17. PMID: 31907348 2. Davidson, S. et al. (2022) Science immunology 7, eabi6763. PMID: 35148201
Note	For research use only

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Datasheet

Anti-Mouse IL24 Recombinant Antibody (SAA2595).pdf

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Anti-Mouse IL24 Recombinant Antibody (SAA2595) (MC472023)

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