Anti-Mouse NKG2D/CD314 Recombinant Antibody (MI-6), APC (MB123137)

Name: Anti-Mouse NKG2D/CD314 Recombinant Antibody (MI-6), APC
Brand: abinScience
SKU: MB123137
Price: 290 USD
Availability: InStock

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Vista general

Número de catálogo	MB123137
Reactividad de especies	Mouse
Aplicaciones	ELISA, FCM
Especie huésped	Rat
Clonalidad	Monoclonal
Isotipo	IgG2a, lambda
ID de clon	MI-6
Conjugación	APC
Objetivo	NKG2-D type II integral membrane protein, Killer cell lectin-like receptor subfamily K member 1, NK cell receptor D, NKG2-D-activating NK receptor, CD314, Klrk1, Nkg2d
Nivel de endotoxinas	Please contact with the lab for this information.
Productos asociados	Rat IgG2a Recombinant Isotype Control Antibody (SPE-7), APC
Número de acceso	O54709
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo	NKG2-D type II integral membrane protein (CD314/KLRK1) is a ~26 kDa protein. Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF.
Nota	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Datasheet

Anti-Mouse NKG2D/CD314 Recombinant Antibody (MI-6), APC.pdf

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