

| Número de catálogo | JN930023 | ||||||
|---|---|---|---|---|---|---|---|
| Reactividad de especies | Mycobacterium tuberculosis | ||||||
| Aplicaciones | ELISA, WB | ||||||
| Especie huésped | Human | ||||||
| Clonalidad | Monoclonal | ||||||
| Isotipo | VHH-hFc | ||||||
| ID de clon | SAA2568 | ||||||
| Objetivo | EC:4.1.3.1, ICL, Isocitrase, Isocitratase, Isocitrate lyase, icl | ||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||
| Pureza | >95% as determined by SDS-PAGE. | ||||||
| Purificación | Protein A/G purified from cell culture supernatant. | ||||||
| Número de acceso | P9WKK7 | ||||||
| Forma | Liquid | ||||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||
| Fondo | Isocitrate lyase (icl1/Isocitrate lyase 1) is a ~47 kDa protein. Involved in the persistence and virulence of M.tuberculosis. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. It could also catalyze the formation of pyruvate and succinate from 2-methylisocitrate, a key step in the methylcitrate cycle (propionate degradation route). 1. Sharma, V. et al. (2000) Nature structural biology 7, 663-8. PMID: 10932251 2. McKinney, JD. et al. (2000) Nature 406, 735-8. PMID: 10963599 3. Kumar, R. et al. (2008) Proteins 72, 892-900. PMID: 18275086 4. Moynihan, MM. et al. (2014) Biochemistry 53, 178-87. PMID: 24354272 | ||||||
| Nota | For research use only |

SDS-PAGE for Anti-Mycobacterium tuberculosis icl1/Isocitrate lyase 1 Antibody (SAA2568)



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