Anti-Mycobacterium tuberculosis icl1/Isocitrate lyase 1 Recombinant Antibody (SAA2568) (JN930023)

Name: Anti-Mycobacterium tuberculosis icl1/Isocitrate lyase 1 Recombinant Antibody (SAA2568)
Brand: abinScience
SKU: JN930023
Price: 126 USD
Availability: InStock

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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

JN930023

Reactivité des espèces

Mycobacterium tuberculosis

Applications

ELISA, WB

Espèce hôte

Human

Clonalité

Monoclonal

Isotype

VHH-hFc

ID de clone

SAA2568

Cible

EC:4.1.3.1, ICL, Isocitrase, Isocitratase, Isocitrate lyase, icl

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P9WKK7

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Isocitrate lyase (icl1/Isocitrate lyase 1) is a ~47 kDa protein. Involved in the persistence and virulence of M.tuberculosis. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. It could also catalyze the formation of pyruvate and succinate from 2-methylisocitrate, a key step in the methylcitrate cycle (propionate degradation route).

1. Sharma, V. et al. (2000) Nature structural biology 7, 663-8. PMID: 10932251

2. McKinney, JD. et al. (2000) Nature 406, 735-8. PMID: 10963599

3. Kumar, R. et al. (2008) Proteins 72, 892-900. PMID: 18275086

4. Moynihan, MM. et al. (2014) Biochemistry 53, 178-87. PMID: 24354272

Note

For research use only

Images

SDS-PAGE

SDS-PAGE for Anti-Mycobacterium tuberculosis icl1/Isocitrate lyase 1 Antibody (SAA2568)

Reférences

Fiche technique

Anti-Mycobacterium tuberculosis icl1/Isocitrate lyase 1 Recombinant Antibody (SAA2568).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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