Anti-NTRK1 Polyclonal Antibody (HY107014)

Name: Anti-NTRK1 Polyclonal Antibody
Brand: abinScience
SKU: HY107014
Price: 168 USD
Availability: InStock

Даташит Поделиться продуктом Копировать информацию

Цена(USD):

Спецификация:

50ug
100ug

Количество:

Свяжитесь с нами

Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HY107014

Описание

Anti-NTRK1 Polyclonal Antibody (HY107014) is a rabbit polyclonal antibody detecting NTRK1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Human

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant human NTRK1 (Asp38-Phe378).

Цель

High affinity nerve growth factor receptor, EC:2.7.10.1, Neurotrophic tyrosine kinase receptor type 1, TRK1-transforming tyrosine kinase protein, Tropomyosin-related kinase A, Tyrosine kinase receptor, Tyrosine kinase receptor A, Trk-A, gp140trk, p140-TrkA, NTRK1, MTC, TRK, TRKA

Уровень эндотоксинов

Please contact with the lab for this information.

Очистка

Purified by antigen affinity column.

Номер доступа

P04629

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

High affinity nerve growth factor receptor (NTRK1) is a ~87 kDa protein. Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand. Can also bind and be activated by NTF3/neurotrophin-3. However, NTF3 only supports axonal extension through NTRK1 but has no effect on neuron survival. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation.

1. Jing, S. et al. (1992) Neuron 9, 1067-79. PMID: 1281417

2. Tacconelli, A. et al. (2004) Cancer cell 6, 347-60. PMID: 15488758

3. Wehrman, T. et al. (2007) Neuron 53, 25-38. PMID: 17196528

4. Klein, R. et al. (1991) Cell 65, 189-97. PMID: 1849459

5. Hempstead, BL. et al. (1991) Nature 350, 678-83. PMID: 1850821

6. Tong, Q. et al. (2012) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 26, 3811-21. PMID: 22649032

7. Anta, B. et al. (2016) The Journal of biological chemistry 291, 19132-45. PMID: 27445338

8. Barker, PA. et al. (1993) The Journal of biological chemistry 268, 15150-7. PMID: 8325889

Примечание

For research use only

Изображения

Ссылки

Даташит