Anti-Human ADCYAP1/PACAP Recombinant Antibody (Lilly patent anti-PACAP) (HB716013)

Name: Anti-Human ADCYAP1/PACAP Recombinant Antibody (Lilly patent anti-PACAP)
Brand: abinScience
SKU: HB716013
Price: 191 USD
Availability: InStock

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Especificación:

50ug
100ug
1mg

Número:

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SDS

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Número de catálogo

HB716013

Descripción

Anti-Human ADCYAP1/PACAP Recombinant Antibody (Lilly patent anti-PACAP) (HB716013) is a human monoclonal antibody detecting ADCYAP1/PACAP in ELISA, FCM, Functional assay. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Human

Aplicaciones

ELISA, FCM, Functional assay

Especie huésped

Human

Clonalidad

Monoclonal

Isotipo

IgG4, kappa

ID de clon

Lilly patent anti-PACAP

Objetivo

Pituitary adenylate cyclase-activating polypeptide, PACAP, PACAP-related peptide, PRP-48, Pituitary adenylate cyclase-activating polypeptide 27, PACAP-27, PACAP27, Pituitary adenylate cyclase-activating polypeptide 38, PACAP-38, PACAP38, ADCYAP1

Nivel de endotoxinas

< 10 EU/mg as determined by LAL method.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

P18509

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Pituitary adenylate cyclase-activating polypeptide (PACAP38) is a ~18 kDa protein. PACAP is a neuropeptide involved in diverse array of physiological processes through activating the PACAP subfamily of class B1 G protein-coupled receptors: VIP receptor 1 (VIPR1), VIP receptor 2 (VIPR2), and PACAP type I receptor (ADCYAP1R1). Exerts neuroprotective and general cytoprotective effects due to anti-apoptotic, anti-inflammatory, and antioxidant actions. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells.

1. Inooka, H. et al. (2001) Nature structural biology 8, 161-5. PMID: 11175907

2. Emery, AC. et al. (2013) Science signaling 6, ra51. PMID: 23800469

3. Wang, J. et al. (2020) Cell research 30, 436-445. PMID: 32047270

4. Piper, SJ. et al. (2022) Nature communications 13, 7013. PMID: 36385145

Nota

For research use only.

Isotype Control

Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)

Imágenes

SDS-PAGE

SDS-PAGE for Anti-PACAP38 Antibody (Lilly patent anti-PACAP)

Referencias

Datasheet

Anti-Human ADCYAP1/PACAP Recombinant Antibody (Lilly patent anti-PACAP).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo

Anti-Human ADCYAP1/PACAP Recombinant Antibody (Lilly patent anti-PACAP) (HB716013)

Vista general

Imágenes

Referencias

Datasheet

SDS