Anti-Phospho-γ-H2AX (pS139) Recombinant Antibody (C6) (HB952013)

Name: Anti-Phospho-γ-H2AX (pS139) Recombinant Antibody (C6)
Brand: abinScience
SKU: HB952013
Price: 126 USD
Availability: InStock

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Precio(USD):

Especificación:

20ug
50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HB952013

Reactividad de especies

Human

Aplicaciones

IHC, IP, WB

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

VHH-mFc (IgG2a)

ID de clon

Objetivo

H2a/x, Histone H2A.X, H2AFX, Histone H2AX, H2AX, gamma H2A.X (phospho S139)

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

P16104

RRID

Anti-Phospho-γ-H2AX (pS139) Antibody (C6) (abinScience Cat# HB952013, RRID:AB_3725742)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Histone H2AX (p-γ-H2AX) is a ~15 kDa protein. Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Phospho-γ-H2AX (pS139) Antibody (C6).

Referencias

Datasheet

Anti-Phospho-γ-H2AX (pS139) Recombinant Antibody (C6).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo