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| カタログ番号 | HB628014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-WT1 Polyclonal Antibody (HB628014) is a rabbit polyclonal antibody detecting WT1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Pig, and Xenopus laevis.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human WT1 (Thr317-Gln446). | ||||||||
| ターゲット | WT1, Wilms tumor protein, WT33 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P19544 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Wilms tumor protein (WT1) is a ~49 kDa protein. Transcription factor that plays an important role in cellular development and cell survival. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. 1. Hamilton, TB. et al. (1995) Nucleic acids research 23, 277-84. PMID: 7862533 2. Stoll, R. et al. (2007) Journal of molecular biology 372, 1227-45. PMID: 17716689 3. Hashimoto, H. et al. (2014) Genes & development 28, 2304-13. PMID: 25258363 4. Smolen, GA. et al. (2004) Cancer research 64, 7846-51. PMID: 15520190 5. Markus, MA. et al. (2006) Experimental cell research 312, 3379-88. PMID: 16934801 6. Weiss, TC. et al. (2009) Biochemistry 48, 148-55. PMID: 19123921 | ||||||||
| 注意事項 | For research use only. |
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