Elezanumab ELISA Kit (DV303018)

Даташит Поделиться продуктом Копировать информацию

Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер	DV303018
Описание	Elezanumab ELISA Kit (DV303018) — Quantitative sandwich ELISA for Elezanumab. Sample: Plasma, Serum. Range: 0.31-5 μg/mL. Sensitivity: 0.156 μg/ml. Highlights ●Sandwich Format — High specificity, reliable quantification. ●High Sensitivity — Optimized for low-abundance target detection. ●Ready-to-Use — Complete kit with pre-coated plates included.
Тип образца	Plasma, Serum
Чувствительность	0.156 μg/ml
Диапазон	0.31-5 μg/mL
Номер доступа	Q96B86
Применения	ELISA
Метод обнаружения	Colorimetric
Тип анализа	Quantitative
Восстановление	80-120%
Доставка	2-8 ℃
Устойчивость и хранение	The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
Характеристики	Elezanumab
Альтернативные названия	ABT-555, AE12-1Y-QL (derived from parental mAb AE12-1 and AE12-1Y), 1791416-49-3
Фон	Repulsive guidance molecule A (Elezanumab) is a ~49 kDa protein. Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses. Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition. Furthermore, RGMA binding to NEO1/neogenin leads to HRAS inactivation by influencing HRAS-PTK2/FAK1-AKT1 pathway. It also functions as a bone morphogenetic protein (BMP) coreceptor that may signal through SMAD1, SMAD5, and SMAD8.
Примечание	For Research Use Only.