

| Número de catálogo | HB058818 |
|---|---|
| Descripción |
HEK293T Human CD142/F3/TF Stable Cell Line (HB058818) is a stable cell line expressing CD142/F3/TF. Engineered for consistent, high-level target expression in research applications.
Highlights
|
| Número de acceso | P13726 |
| Aplicaciones | FCM |
| Especie huésped | HEK293T |
| Especies | Human |
| Objetivo | CD142/F3/TF |
| Propiedades | Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL) |
| Estabilidad y almacenamiento | Frozen in liquid nitrogen. |
| Especificaciones | 1 vial contains at least 2×10^6 cells in 1 mL Freeze Medium |
| Fondo | Tissue factor (CD142/F3) is a ~33 kDa protein. Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. CD142 is the therapeutic target of tisotumab vedotin (Tivdak). |

Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human CD142 monoclonal antibody at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.




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