HEK293T Human CD142/F3/TF Stable Cell Line (HB058818)

Обзор

Каталожный номер	HB058818
Описание	HEK293T Human CD142/F3/TF Stable Cell Line (HB058818) is a stable cell line expressing CD142/F3/TF. Engineered for consistent, high-level target expression in research applications. Highlights ●Stable Expression — Engineered for consistent, high-level target expression.
Номер доступа	P13726
Применения	FCM
Хозяинский вид	HEK293T
Виды	Human
Цель	CD142/F3/TF
Свойства	Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL)
Устойчивость и хранение	Frozen in liquid nitrogen.
Характеристики	1 vial contains at least 2×10^6 cells in 1 mL Freeze Medium
Фон	Tissue factor (CD142/F3) is a ~33 kDa protein. Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. CD142 is the therapeutic target of tisotumab vedotin (Tivdak).

Изображения

Flow cytometry

Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human CD142 monoclonal antibody at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

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