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InVivo Plus Anti-Mouse PD-L1 Antibody(10F.9G2) (MV974049)

InVivo Plus Anti-Mouse PD-L1 Antibody(10F.9G2)
InVivo Plus Anti-Mouse PD-L1 Antibody(10F.9G2)
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Aperçu
Numéro de catalogueMV974049
Description
InVivo Plus Anti-mouse PDL1 Antibody (10F.9G2) [10F.9G2] (MV974049) is a mouse monoclonal antibody detecting PDL1 in in vivo blockade, IF, IHC, FCM, WB, ELISA. Suitable for Mouse.
Highlights
  • ●Multi-Application — Validated across multiple applications.
  • ●Flow Cytometry — Validated for flow cytometry applications.
Reactivité des espècesMouse
Applicationsin vivo blockade, IF, IHC, FCM, WB, ELISA
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG2a, kappa
ID de clone10F.9G2
Cible B7 homolog 1, B7-H1, B7H1, CD274, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, PDL1, Programmed cell death 1 ligand 1, Programmed death ligand 1
Niveau d'endotoxines < 1 EU/mg
Pureté >95% as determined by SDS-PAGE.
Produits associés pH 7.4 Dilution Buffer
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès Q9EP73
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Programmed cell death 1 ligand 1 (PDL1) is a ~32 kDa protein. Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response. Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10).

1. Tamura, H. et al. (2001) Blood 97, 1809-16. PMID: 11238124
2. Freeman, GJ. et al. (2000) The Journal of experimental medicine 192, 1027-34. PMID: 11015443
3. Wang, S. et al. (2003) The Journal of experimental medicine 197, 1083-91. PMID: 12719480
Note For research use only.
Isotype Control Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173) (MF533507)
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  • InVivo Plus Anti-Mouse PD-L1 Antibody(10F.9G2)

    SDS-PAGE

    SDS-PAGE for InVivo Plus Anti-mouse PDL1 Antibody (10F.9G2)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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