InVivoMAb Anti-Human PAUF/ZG16B Antibody (Iv0188) (HB774010)

Name: InVivoMAb Anti-Human PAUF/ZG16B Antibody (Iv0188)
Brand: abinScience
SKU: HB774010
Price: 370 USD
Availability: InStock

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100ug
1mg

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Número de catálogo	HB774010
Descripción	InVivoMAb Anti-Human PAUF Antibody (Iv0188) [Iv0188] (HB774010) is a human monoclonal antibody detecting Pancreatic adenocarcinoma upregulated factor in Blocking, ELISA. Suitable for Human.
Reactividad de especies	Human
Aplicaciones	Blocking, ELISA
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1, kappa
ID de clon	Iv0188
Objetivo	Pancreatic adenocarcinoma upregulated factor, PAUF
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>95% as determined by SDS-PAGE.
Productos asociados	pH 7.4 Dilution Buffer
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	Q96DA0
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo	Pancreatic adenocarcinoma up-regulated factor (PAUF) is a ~18 kDa protein. Functions as a lectin that binds to selective commensal dental plaque bacteria, such as Streptococcus vestibularis. Contributes to maintain homeostasis in the oral microbiome by capturing commensal microbes and regulating their growth using a mucin-assisted clearance mechanism. Plays an important role in pancreatic tumor progression and metastasis. Promotes pancreatic cancer cells migration and invasion through the TLR4/MyD88/NF-kappaB signaling pathway, without the involvement of the TLR4/TRIF pathway. 1. Ghosh, S. et al. (2023) Proceedings of the National Academy of Sciences of the United States of America 120, e2216304120. PMID: 37216558 2. Kim, SA. et al. (2009) Cancer science 100, 828-36. PMID: 19302292 3. Youn, SE. et al. (2022) International journal of molecular sciences 23. PMID: 36232715
Nota	For research use only. Not suitable for clinical or therapeutic use.