

| Каталожный номер | HB774010 |
|---|---|
| Описание |
InVivoMAb Anti-Human PAUF Antibody (Iv0188) [Iv0188] (HB774010) is a human monoclonal antibody detecting Pancreatic adenocarcinoma upregulated factor in Blocking, ELISA. Suitable for Human.
|
| Реактивность видов | Human |
| Применения | Blocking, ELISA |
| Хозяинский вид | Human |
| Клоональность | Monoclonal |
| Изотип | IgG1, kappa |
| ID клона | Iv0188 |
| Цель | Pancreatic adenocarcinoma upregulated factor, PAUF |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >95% as determined by SDS-PAGE. |
| Связанные продукты | pH 7.4 Dilution Buffer |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | Q96DA0 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Фон | Pancreatic adenocarcinoma up-regulated factor (PAUF) is a ~18 kDa protein. Functions as a lectin that binds to selective commensal dental plaque bacteria, such as Streptococcus vestibularis. Contributes to maintain homeostasis in the oral microbiome by capturing commensal microbes and regulating their growth using a mucin-assisted clearance mechanism. Plays an important role in pancreatic tumor progression and metastasis. Promotes pancreatic cancer cells migration and invasion through the TLR4/MyD88/NF-kappaB signaling pathway, without the involvement of the TLR4/TRIF pathway. 1. Ghosh, S. et al. (2023) Proceedings of the National Academy of Sciences of the United States of America 120, e2216304120. PMID: 37216558 2. Kim, SA. et al. (2009) Cancer science 100, 828-36. PMID: 19302292 3. Youn, SE. et al. (2022) International journal of molecular sciences 23. PMID: 36232715 |
| Примечание | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for InVivoMAb Anti-Human PAUF Antibody (Iv0188)



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