Recombinant Human CD218a/IL18R1 Protein, C-His (HC691021) expressed in Mammalian Cells, spanning Ala19-Arg329. Purity: >90% by SDS-PAGE.
Highlights
●His-Tagged — N-terminal 6×His tag for IMAC purification.
●Mammalian Expression — Proper folding and native glycosylation.
●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессии
Mammalian cells
Номер доступа
Q13478
Длина белка
Ala19-Arg329
Применения
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды
Homo sapiens (Human)
Характер
Recombinant
Уровень эндотоксинов
Please contact with the lab for this information.
Чистота
>90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса
38.67 kDa
Форма
Lyophilized
Буфер хранения
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия
CD218 antigen-like family member A, CD218a, CDw218a, EC:3.2.2.6, IL-18R-1, IL-18R-alpha, IL-18R1, IL-18Ralpha, IL-1Rrp, IL1 receptor-related protein, IL18R1, IL1R-rp, IL1RRP, Interleukin-18 receptor 1, Interleukin-18 receptor alpha
Фон
Interleukin-18 receptor 1 is a ~62 kDa protein. Within the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor IL1B. Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells. Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3.
1. Kato, Z. et al. (2003) Nature structural biology 10, 966-71. PMID: 14528293
2. Wei, H. et al. (2014) FEBS letters 588, 3838-43. PMID: 25261253
3. Tsutsumi, N. et al. (2014) Nature communications 5, 5340. PMID: 25500532
中文
English
한국어
日本語
Español
Français
Русский
