Anti-Human CD218a/IL18R1 Recombinant Antibody (1G12), FITC (HC691117)

Name: Anti-Human CD218a/IL18R1 Recombinant Antibody (1G12), FITC
Brand: abinScience
SKU: HC691117
Price: 223 USD
Availability: InStock

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Overview

Catalog No.	HC691117
Species reactivity	Human
Applications	FCM
Host species	Mouse
Isotype	IgG1, kappa
Clone ID	1G12
Conjugation	FITC
Clonality	Monoclonal
Target	CD218a, IL-18R1, IL18R1, CDw218a, IL-18R-alpha, IL-18R-1, Interleukin-18 receptor 1, IL-18Ralpha, IL1 receptor-related protein, CD218 antigen-like family member A, IL-1Rrp, IL1RRP, IL1R-rp, Interleukin-18 receptor alpha
Endotoxin level	Please contact with the lab for this information.
Associated products	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), FITC
Accession	Q13478
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Interleukin-18 receptor 1 (CD218a/IL18R1) is a ~62 kDa protein. Within the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor IL1B. Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells. Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3. 1. Kato, Z. et al. (2003) Nature structural biology 10, 966-71. PMID: 14528293 2. Wei, H. et al. (2014) FEBS letters 588, 3838-43. PMID: 25261253 3. Tsutsumi, N. et al. (2014) Nature communications 5, 5340. PMID: 25500532 4. Shi, X. et al. (2023) Nature 624, 442-450. PMID: 37993714 5. Parnet, P. et al. (1996) The Journal of biological chemistry 271, 3967-70. PMID: 8626725 6. Tominaga, K. et al. (2000) International immunology 12, 151-60. PMID: 10653850
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Datasheet

Anti-Human CD218a/IL18R1 Recombinant Antibody (1G12), FITC.pdf

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Anti-Human CD218a/IL18R1 Recombinant Antibody (1G12), FITC (HC691117)

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